Actively Recruiting

Phase Not Applicable
Age: 14Years - 25Years
All Genders
NCT05664412

Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

Led by Stephan Eliez · Updated on 2025-12-02

40

Participants Needed

1

Research Sites

166 weeks

Total Duration

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AI-Summary

What this Trial Is About

The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion. The main aim of the present research project is to investigate the effects of repeated, individually tuned high-density (HD) tACS on cognition (i.e., WM performance) and related neuroimaging markers in carriers of the 22q11DS. As cognitive deficits, most notably WM impairment, are among the earliest signs of psychotic disorders, interventions during adolescence aimed at reducing cognitive decline in at-risk individuals may prove effective in delaying or even preventing the later emergence of psychotic symptoms.

CONDITIONS

Official Title

Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

Who Can Participate

Age: 14Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed genetic diagnosis of 22q11DS
  • Age between 14 and 25 years old
  • Willingness to participate
  • Informed Consent signed by the subject and/or the caregiver(s)
Not Eligible

You will not qualify if you...

  • Epilepsy
  • Deep brain stimulation electrodes
  • Traumatic brain injury
  • Facial metal implants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Geneva

Geneva, Canton of Geneva, Switzerland, 1200

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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