Actively Recruiting
Role of Uterine Artery Doppler Indices and Sonographic Measurement of Uterocervical Angle in Predicting Preterm Labor
Led by Kafrelsheikh University · Updated on 2026-05-18
47
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well uterine artery Doppler indices combined with uterocervical angle measurements can predict preterm labor in pregnant women. The study focuses on women between 24 and 34 weeks of pregnancy who are at risk of preterm labor, particularly those experiencing threatened preterm labor. The investigation seeks to determine if using both these ultrasound measurements together improves the accuracy in identifying women likely to have preterm labor. Participants will undergo two types of ultrasound measurements during their antenatal care between 24 and 34 weeks of gestation. The uterine artery Doppler indices will be measured using a transabdominal ultrasound approach, while the anterior uterocervical angle will be assessed via transvaginal ultrasound. These combined measurements are studied to better predict preterm labor compared to using either method alone. During the study, participants will have these ultrasound assessments added to their routine prenatal visits. Researchers will evaluate the sensitivity, specificity, and accuracy of these measurements in predicting preterm labor. The study includes pregnant women aged 18 to 40 with singleton pregnancies and confirmed gestational age by first trimester ultrasound. Participants will be monitored to see how well these ultrasound indicators detect preterm labor, enhancing early identification and care.
CONDITIONS
Brief Title
Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm Labor
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient who will give verbal & written informed consent.
- Pregnant women between 18 and 40 years old.
- Singleton pregnancy.
- Gestational age confirmed by first trimester ultrasound scan (<14 weeks).
- Gestational age between 24 and 34 weeks.
- Threatened preterm labor defined as at least one uterine contraction every 10 minutes lasting ≥30 seconds, cervical dilatation ≤3 cm, and cervical effacement <80%.
You will not qualify if you...
- Ruptured membranes.
- Clinical evidence of chorioamnionitis.
- Fetal compromise on evaluation.
- Severe obstetric complications such as severe preeclampsia or eclampsia.
- Diagnosed intrauterine growth restriction (IUGR).
- Congenital fetal anomalies.
- Multiple pregnancies.
- Prior cervical surgery (e.g., cone biopsy, cerclage).
- Significant maternal medical disorders like chronic hypertension, diabetes mellitus, or liver dysfunction.
- Severe non-obstetric complications such as acute abdomen.
AI-Screening
AI-Powered Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 10 weeks between 24 and 34 weeks of pregnancy
Participants undergo transabdominal ultrasound to measure uterine artery Doppler indices and transvaginal ultrasound to measure the uterocervical angle between 24 and 34 weeks of gestation.
1 to 2 visits depending on ultrasound measurements
Duration - Until delivery
Participants are observed to assess the predictive value of ultrasound measurements for preterm labor outcomes.
Trial Site Locations
Total: 1 location
1
Kafr elsheikh university hospital
Kafr ash Shaykh, Egypt
Actively Recruiting
Research Team
N
Nourhan M Shalaby, Master
A
Ahmed M Fathy, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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