Actively Recruiting

Phase Not Applicable
Age: 40Years - 55Years
MALE
NCT05384535

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Led by Northwell Health · Updated on 2025-11-24

100

Participants Needed

1

Research Sites

324 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine whether using bpMRI in subjects who are at high risk of developing prostate cancer in conjunction with PSA will improve prostate cancer screening protocols.

CONDITIONS

Official Title

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

Who Can Participate

Age: 40Years - 55Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • PSA between 1.0 and 2.5 ng/dL
  • High risk for prostate cancer, such as being Black or having a first-degree relative with prostate cancer (father or brother) or specific genetic syndromes (BRCA 1/2, HOX B13, Lynch syndrome, ATM, CHEK2)
  • Willingness to participate in prostate cancer screening
  • Ability to provide informed consent
Not Eligible

You will not qualify if you...

  • Nodularity or firmness of prostate on exam
  • Previous prostate biopsy or prostate surgery
  • Current use of 5-alpha reductase inhibitors for benign prostatic hyperplasia
  • History of urinary tract infection or prostatitis within the past 6 months
  • Contraindications to MRI including pacemakers, neurostimulators, metal cardiac valves, certain tattoos, or foreign bodies
  • Claustrophobia, anxiety, or vertigo when inside the MRI scanner
  • Inability to lie flat for the duration of the MRI study

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Cynthia Knauer

Lake Success, New York, United States, 11042

Actively Recruiting

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Research Team

C

Cynthia Knauer, RN

CONTACT

M

Monica Johnson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

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Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort | DecenTrialz