Actively Recruiting
Utility of PCD Diagnostics to Improve Clinical Care
Led by Connecticut Children's Medical Center · Updated on 2025-09-22
50
Participants Needed
1
Research Sites
267 weeks
Total Duration
On this page
Sponsors
C
Connecticut Children's Medical Center
Lead Sponsor
U
UConn Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
This cross-sectional and longitudinal observational study is to gather data on the utility of tests that are used to make a diagnosis of primary ciliary dyskinesia (PCD). There is new testing available, called nasal nitric oxide testing, that non-invasively measures nitric oxide levels in the sinus cavity. Individuals with PCD characteristically have low levels, but this testing does not have extensive data from everyday clinical practice. The objective of this proposal is to improve the diagnostic approach to children and adults with clinical concerns for primary ciliary dyskinesia (PCD).
CONDITIONS
Official Title
Utility of PCD Diagnostics to Improve Clinical Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 2 years or older
- Must have at least two of the following: neonatal respiratory distress, chronic nasal congestion or runny nose, chronic cough, situs or laterality defects, bronchiectasis
- Ability to provide informed consent or have consent provided by a parent or guardian
You will not qualify if you...
- Recent sinus surgery or bloody nose within the past week
- Age under 2 years
- Unable to tolerate nasal probe for testing
- Currently being treated with antibiotics for sinusitis or other respiratory infection
- Hospitalized for respiratory exacerbation
- Unable or unwilling to provide informed consent
- Any other reason investigator deems participant unsuitable for testing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Pulmonary Division
Hartford, Connecticut, United States, 06111
Actively Recruiting
Research Team
M
Melanie S Collins, MD
CONTACT
S
Sigrid M Almeida, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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