Actively Recruiting

Phase Not Applicable
Age: 8Years - 18Years
All Genders
NCT05553899

Utility of PET-MRI in Surveillance of Paediatric Brain Tumours

Led by Sheffield Children's NHS Foundation Trust · Updated on 2026-05-06

5

Participants Needed

1

Research Sites

169 weeks

Total Duration

On this page

Sponsors

S

Sheffield Children's NHS Foundation Trust

Lead Sponsor

G

GE Healthcare

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a pilot project to explore the utility of PET-MRI in the post-treatment surveillance of high-grade gliomas or medulloblastomas in children in our institution.

CONDITIONS

Official Title

Utility of PET-MRI in Surveillance of Paediatric Brain Tumours

Who Can Participate

Age: 8Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a presumptive or histologically confirmed diagnosis of a malignant brain tumour requiring treatment
  • Diagnostic uncertainty about tumour recurrence post-treatment based on conventional MR imaging in the opinion of the MDT
  • Have a life expectancy of at least three months
  • Able to comply with an MRI scan without a general anaesthetic
Not Eligible

You will not qualify if you...

  • Unable to comply with an MRI scan without a general anaesthetic
  • Diabetes or other causes of hyperglycaemia
  • Pregnancy
  • Patient body habitus above scanner dimensions
  • Standard contra-indication to MRI (eg. pacemaker, non-compatible metallic implants, altered renal function)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Sheffield Children's Hospital

Sheffield, South Yorkshire, United Kingdom, S10 1SN

Actively Recruiting

Loading map...

Research Team

D

David King, MBChB

CONTACT

K

Keith Pugh, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here