Actively Recruiting

Phase 4
Age: 18Years +
All Genders
Healthy Volunteers
NCT06514547

Vaccine Immunity and Inflammation in the Aging Person Living With HIV

Led by Hennepin Healthcare Research Institute · Updated on 2025-06-12

250

Participants Needed

1

Research Sites

259 weeks

Total Duration

On this page

Sponsors

H

Hennepin Healthcare Research Institute

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.

CONDITIONS

Official Title

Vaccine Immunity and Inflammation in the Aging Person Living With HIV

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age6518 years
  • HIV diagnosis
  • On antiretroviral therapy with HIV viral load under 200 within the last year
  • Controls must be HIV antibody-negative and age 6518 years
Not Eligible

You will not qualify if you...

  • Other significant immunosuppressing conditions
  • Age under 18 years
  • Pregnancy at enrollment
  • Contraindication to pneumococcal vaccination
  • Severe anemia with last hemoglobin below 8 g/dl
  • Known contraindication to non-clinical blood draws
  • Potential non-adherence to study procedures as judged by investigator
  • Adults unable or impaired to consent
  • Incarceration at time of enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hennepin Healthcare System

Minneapolis, Minnesota, United States, 55415

Actively Recruiting

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Research Team

A

Anne Frosch, MD

CONTACT

M

Marya Abd El Hadi, BSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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