Study of Vaginal Cuff Anesthesia Using Bupivacaine to Reduce Pain After Hysterectomy

What this Trial Is About

Researchers are studying whether injecting a local anesthetic called Bupivacaine with epinephrine into the vaginal cuff before closure during total laparoscopic hysterectomy can reduce the need for immediate postoperative pain medication and improve patient comfort and satisfaction. This randomized, quadruple-masked study focuses on women aged 18 and older undergoing hysterectomy for benign conditions. Participants receive either an injection of Bupivacaine with epinephrine or a saline placebo at four points around the vaginal cuff before closure using a sterilized needle. Each injection delivers 5cc of the assigned solution to a depth of 3-4 cm. The study compares postoperative pain medication use and patient-reported pain scores within the first four hours after surgery. During the study, researchers measure the amount of opioid pain medication in morphine equivalents and non-opioid analgesics used, along with changes in patients pain scores from baseline to four hours after treatment. Monitoring includes assessing patient comfort and medication use immediately following surgery. Participation involves a single surgical procedure with postoperative follow-up lasting four hours for outcome measurement.

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use