Actively Recruiting
Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women
Led by Lallemand Health Solutions · Updated on 2025-11-26
72
Participants Needed
1
Research Sites
32 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the present study is to obtain more information on the transit of orally ingested probiotics to the vagina.
CONDITIONS
Official Title
Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinically healthy female between 18 and 50 years old, inclusive
- Have a regular or predictable menstrual cycle
- Typically have regular bowel movements
- Willing and able to take a probiotic supplement daily for 4 weeks
- Willing to stop taking probiotic supplements and probiotic-fortified products 2 weeks before and during the study
- Willing to stop taking fiber supplements 2 weeks before and during the study
- Willing to provide 1 stool sample 4 times during the study
- Willing to provide 2 vaginal swabs 4 times during the study
- Willing to undergo vaginal pH swab measurements 5 times during the study
- Willing to provide 2 perineal skin swabs 3 times during the study
- Willing to complete a pregnancy test at screening
You will not qualify if you...
- Menopausal women
- Vaginal pH less than 2 or greater than 5 at screening
- Menstruation during sample collection times
- Women who are lactating, pregnant, trying to get pregnant, or have a positive pregnancy test
- Use of vaginal probiotics in the last 3 months
- Use of vaginal antibiotics or antifungals in the last 3 months
- Use of oral antibiotics or antifungals in the last month
- Ongoing symptoms of vaginal or urinary tract infections
- Treatment for vaginal sepsis or urosepsis
- Currently treated for severe chronic diseases such as cancer, renal failure, chronic inflammatory digestive or gastrointestinal diseases, or immunodeficiency
- Clinical diagnosis of gynecological diseases such as fibroma, endometriosis, or polycystic ovarian syndrome
- Clinical diagnosis of secondary dysmenorrhea
- Intolerance, allergy, or sensitivity to milk, soy, or yeast
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Evalulab
Montreal, Canada
Actively Recruiting
Research Team
J
Jenna Bouassaly, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
OTHER
Number of Arms
3
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