Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT07359755

Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study

Led by University of Sao Paulo General Hospital · Updated on 2026-01-22

86

Participants Needed

1

Research Sites

245 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women. The main questions it seeks to answer are: * Is the objective cure rate for vaginal mesh surgery non-inferior to that of the abdominal approach? * Is the use of vaginal mesh as safe as abdominal mesh?

CONDITIONS

Official Title

Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with stage II or higher apical compartment genital prolapse
  • Patients with a medical indication for surgical correction
  • Patients willing and able to provide informed consent and complete outcome assessments
Not Eligible

You will not qualify if you...

  • Patients unable or unwilling to complete validated outcome assessment instruments
  • Patients requiring additional surgical procedures that may change pelvic floor anatomy (e.g., hysterectomy)
  • Patients with prior pelvic radiotherapy
  • Patients with congenital or acquired anomalies of the urogenital or gastrointestinal systems
  • Patients with medical conditions contraindicating elective surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital das Clinicas da Faculdade de Medicina de Sao Paulo

São Paulo, São Paulo, Brazil, 05403000

Actively Recruiting

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Research Team

M

Marcelo Hisano, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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