Actively Recruiting

Phase 2
Phase 3
Age: 18Years - 99Years
All Genders
NCT07079735

Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant

Led by Columbia University · Updated on 2025-09-25

150

Participants Needed

2

Research Sites

174 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

C

Cornell University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to compare the safety and efficacy of letermovir with valganciclovir for prevention of Cytomegalovirus (CMV) viremia in moderate to high risk serostatus heart transplant recipients.

CONDITIONS

Official Title

Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients older than 18 years who have received a heart transplant and have not started CMV prophylaxis
Not Eligible

You will not qualify if you...

  • History of or suspected CMV disease within 6 months prior to enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

NYP-Weill Cornell

New York, New York, United States, 10021

Actively Recruiting

2

Columbia University/NYP Milstein Hospital

New York, New York, United States, 10032

Actively Recruiting

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Research Team

A

Afsana Rahman, MD

CONTACT

A

Adel T Alnatour, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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