Actively Recruiting
Validating a Blood Test for the Detection of Traumatic Brain Injury in Children
Led by University of Nebraska · Updated on 2025-07-30
330
Participants Needed
1
Research Sites
133 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this study is to establish if Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin C-terminal Hydrolase L1 (UCH-L1) are predictive of computed tomography (CT) findings in pediatric traumatic brain injuries (TBI). The participant population is pediatric patients, ages 0 to less than 18 years old with a possible TBI or trauma-related injury who have blood drawn per standard of care in the emergency department. Blood samples will be analyzed using the i-STAT TBI cartridge (Abbott Laboratories, Abbott Park, IL, USA) by the Emergency Department charge nurse within one hour of collection of the blood sample. Clinical outcomes will be assessed via telephone interview with a parent at 3 and 6 months for all surviving TBI patients.
CONDITIONS
Official Title
Validating a Blood Test for the Detection of Traumatic Brain Injury in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant is between 0 and 17 years old
- Presented with non-penetrating trauma
- Blood sample was drawn within 24 hours of injury
- Head CT or MRI scan was obtained for TBI group
You will not qualify if you...
- Presentation to the hospital more than 24 hours after injury
- Participant is 18 years old or older
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's Nebraska
Omaha, Nebraska, United States, 68114
Actively Recruiting
Research Team
M
Megan McChesney, BSN, RN, CPN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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