Testing the Creyos Online Cognitive Assessment in Older Adults with Mild Cognitive Impairment or Remitted Major Depressive Disorder

What this Trial Is About

Researchers are evaluating the Creyos online cognitive assessment platform in older adults who have mild cognitive impairment MCI or major depressive disorder in remission rMDD. This observational study aims to confirm the feasibility of using the Creyos battery in these groups and to see if it can detect cognitive changes that predict outcomes on traditional paper-and-pencil neuropsychological tests over a period of up to five years. Participants are divided into three groups those diagnosed with MCI, individuals with remitted major depressive disorder without current symptoms, and healthy controls with no psychiatric history or psychotropic medication use. They will complete the Creyos online cognitive tests every three months and undergo yearly in-person neuropsychological testing to compare results over time. During the study, participants will be assessed quarterly with the Creyos platform and yearly with standard cognitive tests for up to five years. Researchers will monitor how well the Creyos battery works in these populations, looking at feasibility and validity of the online tests in detecting cognitive changes. The study involves regular evaluations, including cognitive assessments conducted both online and in person, with participant involvement spanning up to five years.

Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment