Actively Recruiting

Age: 18Years +
All Genders
NCT04662918

Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding

Led by Xingshun Qi · Updated on 2025-10-07

3000

Participants Needed

23

Research Sites

204 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Acute gastrointestinal bleeding is potentially lethal in liver cirrhosis. Accurate assessment of prognosis is critical in a timely fashion. A novel model, CAGIB score, has been developed based on our Chinese multicenter retrospective study. Now, a prospective, international multicenter, observational study will be performed to further compare the performance of CAGIB versus Child-Pugh and MELD scores for evaluating the in-hospital mortality of patients with liver cirrhosis and acute gastrointestinal bleeding.

CONDITIONS

Official Title

Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  1. Patients with liver cirrhosis;
  2. Patients with acute gastrointestinal bleeding presenting with hematemesis, melena, and/or hematochezia;
  3. Adults (age≥18 years old).
Not Eligible

You will not qualify if you...

  1. Components of Child-Pugh, MELD, and CAGIB scores are not available;
  2. In-hospital outcomes are not evaluable.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 23 locations

1

The Wright Center for Graduate Medical Education, 501 S. Washington Avenue

Scranton, Pennsylvania, United States, 18503

Not Yet Recruiting

2

São Paulo State University (UNESP), Botucatu Medical School

São Paulo, São Paulo, Brazil

Actively Recruiting

3

Beijing Youan Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Actively Recruiting

4

The Seventh Medical Center of Chinese PLA General Hospital

Beijing, Beijing Municipality, China

Not Yet Recruiting

5

First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

Actively Recruiting

6

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Actively Recruiting

7

First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China

Actively Recruiting

8

The Six People's Hospital of Dalian

Dalian, Liaoning, China

Actively Recruiting

9

Air Force Hospital of Northern Theater Command

Shenyang, Liaoning, China

Actively Recruiting

10

General Hospital of Northern Theater Command

Shenyang, Liaoning, China

Actively Recruiting

11

The First Hospital of China Medical University

Shenyang, Liaoning, China

Actively Recruiting

12

The Six People's Hospital of Shenyang

Shenyang, Liaoning, China

Actively Recruiting

13

Tangdu Hospital, Fourth Military Medical University,

Xi'an, Shaanxi, China

Actively Recruiting

14

The First Affiliated Hospital of Xi'an Jiao Tong University

Xi'an, Shaanxi, China

Actively Recruiting

15

The Second Affiliated Hospital of Xi'an Jiao Tong University

Xi'an, Shaanxi, China

Actively Recruiting

16

Xi'an Central Hospital

Xi'an, Shaanxi, China

Actively Recruiting

17

Shandong Provincial Hospital

Jinan, Shandong, China

Actively Recruiting

18

Cathay General Hospital, Fu-Jen Catholic University School of Medicine

Taibei, Taiwan, China

Not Yet Recruiting

19

Charité University Medical Center

Berlin, State of Berlin, Germany

Actively Recruiting

20

Ernakulam Medical Center

Kochi, Kochi, India

Not Yet Recruiting

21

Azienda di Rilievo Nazionale ad Alta Specializzazione Civico-Di Cristina-Benfratelli

Palermo, Palermo, Italy

Actively Recruiting

22

National Autonomous University of Mexico

Mexico City, Mexico City, Mexico

Actively Recruiting

23

Bezmialem Vakif University

Istanbul, Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

X

Xingshun Qi, Dr.

CONTACT

Z

Zhaohui Bai, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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