Actively Recruiting
Validation of the Efficacy of Air Purifiers in Indoor Environment and Allergic Symptoms in Allergic Rhinitis Patients
Led by Yonsei University · Updated on 2025-03-24
44
Participants Needed
1
Research Sites
14 weeks
Total Duration
On this page
Sponsors
Y
Yonsei University
Lead Sponsor
L
LG Electronics Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study targets adult patients between the ages of 19 and 60 who were diagnosed with allergic rhinitis caused by indoor inhalation antigens. Patients with moderate to severe and persistent allergic rhinitis who continue to require medication such as antihistamines and nasal spray steroids for allergic rhinitis are the subjects of this study. Patients who participate in the study will install air purifiers for a certain period of time and observe the objective and subjective improvement of rhinitis symptoms. The study is conducted on two separate occasions for four weeks, and there is a two-week period between the two periods of no use of air purifiers. There are two types of air purifiers: 1)It is an air purifier with a HEPA filter and a VOC filter, and 2) a fake air purifier without air cleaning function. Subjects are divided into Group A and Group B. Group A will receive a fake air purifier, and Group B will be assigned an air purifier with a HEPA + VOC collecting filter. After using the assigned air purifier for the first four weeks, you will have a period of not using it for two weeks, and then replace the air purifiers with each other and use it again for four weeks. When you first assign an air purifier, you will receive an air purifier with a certain filter It is randomly assigned without knowing whether both the researcher and the patient will receive a regular period. During the study period, patients need to visit three times, including when registering for the study, and the study period is screened It will take about 5 months from the end of the air purifier operation
CONDITIONS
Official Title
Validation of the Efficacy of Air Purifiers in Indoor Environment and Allergic Symptoms in Allergic Rhinitis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 19 to 60 years
- Diagnosed with moderate to severe persistent allergic rhinitis by an allergy specialist or otolaryngologist
- Stable treatment without changes for more than one month
- Total nasal symptom score of 8 or higher
- Allergic rhinitis caused by indoor inhalation antigens (house dust mites or pet allergens)
- Spend at least 8 hours per day at home where the purifier will be installed
- Home has Wi-Fi installed
- Can read and write Korean
- Willing to participate and provide written informed consent
You will not qualify if you...
- Sensitized to seasonal allergens such as tree, grass, or weed pollen
- Rhinitis caused by non-allergic factors (drug, vascular, infectious rhinitis, etc.)
- Used systemic steroids for more than 2 weeks in the last 3 months
- Taking antihistamines for conditions other than rhinitis (e.g., chronic urticaria)
- Anatomical nasal abnormalities causing congestion
- Planning to move or be away from home for 5 or more consecutive days during the study
- Used an air purifier within the last 3 months
- Pregnant or breastfeeding women
- Persons lacking decision-making capacity or residing in care facilities
- Deemed unfit for clinical research participation by the investigator
AI-Screening
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Trial Site Locations
Total: 1 location
1
Yonsei University
Seoul, South Korea, 03722
Actively Recruiting
Research Team
K
Kyung Hee Park
CONTACT
I
Im Shin
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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