Actively Recruiting
Validation of High-Throughput Large-Format Tissue Preprocessing for Lung and Colorectal Cancer
Led by Nanfang Hospital, Southern Medical University · Updated on 2026-02-10
1000
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This project aims to employ a sample preprocessing system in conjunction with three-dimensional imaging techniques to generate morphologically more complete, high-resolution datasets for lung and colorectal cancers. Building on systematic experimental optimization of the preprocessing system, the investigators will establish tissue-clearing workflows and transparency assessment criteria specifically for lung and colorectal cancer specimens, and develop and validate an efficient 3D immunofluorescent iterative staining protocol adapted for these tumor types to achieve robust three-dimensional imaging. Successful implementation of this project will enable an in-depth characterization of the spatial morphological features of lung and colorectal cancer pathology, facilitate identification of more effective and precise interventional strategies, and ultimately contribute to improved overall survival for cancer patients. Additionally, the resulting datasets will support prospective validation of two-dimensional pathological models.
CONDITIONS
Official Title
Validation of High-Throughput Large-Format Tissue Preprocessing for Lung and Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have been pathologically diagnosed as having lung cancer or colorectal cancer.
- Patients with complete clinical data and tumor tissue materials, including H&E slides, paraffin blocks, and discarded ex vivo specimens.
You will not qualify if you...
- Patients with missing data or specimens not meeting quality control requirements for analysis.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China, 510515
Actively Recruiting
Research Team
Z
Zhengyu Zhang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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