Actively Recruiting
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
Led by Brigham and Women's Hospital · Updated on 2025-12-05
150
Participants Needed
2
Research Sites
242 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
M
Mclean Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.
CONDITIONS
Official Title
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy individuals aged 18 to 65
- Body mass index (BMI) between 20 and 35.0 kg/m2
- Normal or corrected-to-normal vision
- Good general health
- Able to understand and willing to sign written informed consent
You will not qualify if you...
- Current or past medical conditions
- Current or past eating disorder
- On a restricted diet or taking weight loss medications
- History of bariatric surgery
- Weight change greater than 3% in the past 3 months
- Recent illicit recreational drug abuse
- Current nicotine use
- Intellectual disability
- Conditions increasing risks from TMS or MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
McLean Hospital
Belmont, Massachusetts, United States, 02478
Actively Recruiting
2
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02120
Actively Recruiting
Research Team
L
Laura Holsen, PhD
CONTACT
M
Mark Halko, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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