Actively Recruiting

Age: 18Years +
All Genders
NCT04007783

Validation of the O-bridge Protocol: a Prospective, Multicenter Trial

Led by AZ Sint-Jan AV · Updated on 2022-02-24

80

Participants Needed

5

Research Sites

560 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Surgical reconstruction to restore oral function and aesthetics after major ablative surgery in the oral cavity forms a challenge to maxillofacial surgeons, and greatly impacts patient' quality of life (QOL). The "Oncological-bridge (O-bridge®)" protocol, which offers (immediate/delayed) fixed prosthetic rehabilitation in a minimum of sessions and a strongly reduced two-week treatment time.

CONDITIONS

Official Title

Validation of the O-bridge Protocol: a Prospective, Multicenter Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a confirmed diagnosis of osteonecrosis of the jaw (ORN or MRONJ) or a benign or malignant tumor in the oral cavity or jaw bone requiring jaw resection
  • Patients eligible for jaw and oral cavity reconstruction combined with immediate or delayed implant loading for fixed prosthetic rehabilitation
  • Patients not eligible for conventional removable prosthetic rehabilitation
Not Eligible

You will not qualify if you...

  • Patients not meeting the above inclusion criteria
  • Patients with osteonecrosis not related to cancer diagnosis or treatment
  • Patients with medical reasons preventing jaw reconstruction with immediate implant loading for fixed prosthetic rehabilitation
  • Patients whose primary language is not Dutch or English will be excluded from acoustic speech evaluation, though speech intelligibility can still be assessed

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Ziekenhuis Netwerk Antwerpen

Antwerp, Belgium

Actively Recruiting

2

ZMACK association - Antwerp University Hospital

Antwerp, Belgium

Actively Recruiting

3

Division of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende AV

Bruges, Belgium

Actively Recruiting

4

University Hospital Leuven

Leuven, Belgium

Actively Recruiting

5

AZ Nikolaas

Sint-Niklaas, Belgium

Actively Recruiting

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Research Team

A

Araceli Diez-Fraile, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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