Actively Recruiting
Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II)
Led by Instituto de Investigacion Sanitaria La Fe · Updated on 2025-12-19
200
Participants Needed
1
Research Sites
133 weeks
Total Duration
On this page
Sponsors
I
Instituto de Investigacion Sanitaria La Fe
Lead Sponsor
H
Hospital Universitario La Fe
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial investigates the sentinel lymph node (SLN) technique as a less invasive alternative to conventional lymphadenectomy in patients with early-stage ovarian cancer. The primary objective is to evaluate the effectiveness, safety, and diagnostic accuracy of the SLN approach in detecting lymphatic metastases. By assessing its negative predictive value, the study aims to determine whether the SLN technique can reliably replace systematic pelvic and paraaortic lymphadenectomy. If successful, this technique could minimize surgical morbidity, shorten hospitalization stays, and lower complication rates, ultimately improving patient outcomes.
CONDITIONS
Official Title
Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent before any trial procedure
- Female, 18 years or older at inclusion
- Histopathological diagnosis of malignant ovarian tumor in early stage FIGO I-II, planned for staging surgery
- Suspected malignant ovarian tumor in early stage FIGO I-II undergoing exploratory laparotomy and biopsy, followed by staging surgery if positive
You will not qualify if you...
- Failure to give or revocation of informed consent
- Under 18 years old at inclusion
- Previous vascular surgery on aorta, vena cava, or pelvic vessels
- Previous pelvic or paraaortic lymphatic surgery
- History of lymphoma
- Previous abdomino-pelvic tumor
- Allergy to Tc99 or ICG
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital Universitario y Politécnico La Fe
Valencia, Valencia, Spain, 46026
Actively Recruiting
Research Team
M
Mónica Cebrián Coordinator Clinical Research Area
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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