Actively Recruiting

Age: 18Years +
All Genders
NCT07300306

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Led by Marmara University · Updated on 2026-05-08

2500

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of sepsis in adult patients admitted to Intensive Care Units (ICUs) in Turkey. The main questions it aims to answer are: * Does the SOFA-2 score accurately predict 30-day mortality in ICU patients? * What is the prevalence of Sepsis-3 and septic shock in Turkish ICUs? Researchers will compare the new SOFA-2 score to the existing SOFA-1 score to see if the new score provides better predictive accuracy for patient outcomes. Participants will not receive any experimental intervention. Researchers will collect data from routine medical care, including: * Vital signs, laboratory test results, and details of organ support (such as mechanical ventilation or dialysis) during the first 24 hours of admission. * Survival status at 30 days.

CONDITIONS

Official Title

Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older.
  • Admitted to the Intensive Care Unit (ICU) during the study recruitment window.
  • For the Validation Cohort: Stay in the ICU for at least 24 hours.
  • For the Point Prevalence Cohort: Present in the ICU at 08:00 AM on the designated Index Day or admitted within the following 24 hours.
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years old.
  • Patients admitted to Pediatric Intensive Care Units.
  • Patients admitted to Coronary Care Units (CCU).
  • Patients admitted to Cardiovascular Surgery Intensive Care Units.
  • Patients admitted only for organ donation.
  • Patients with missing core data needed for score calculation.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Marmara University Pendik Training and Research Hospital

Istanbul, Turkey (Türkiye), 34912

Actively Recruiting

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Research Team

M

Mustafa Kemal Arslantaş, Prof. Dr.

CONTACT

F

Fethi Gül, Assoc. Prof.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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