Actively Recruiting

Age: 18Years +
All Genders
NCT06549179

Validation Study of the Performance of the French Version of the Autism Mental Status Examination Scale as a Tool for Identifying Autism Spectrum Disorder in Adults

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-25

410

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To improve diagnosis of Autism Spectrum Disorder (ASD), expert centers have been set up in France since 2000/2010. However, waiting times in these centers are long, mean of 19 months for adults, and more than half the people seen do not end up with an ASD, even though referral by a psychiatrist is increasingly required. Therefore, validated diagnostic tools for screening before referral are needed. The Autism Mental Status Exam (AMSE), a 8-item tool, which is quick and easy to use, appears to have excellent sensitivity (0.91) and specificity (0.93). However, this tool was only evaluated when used by experts and on a sample of 50 patients. The hypothesis of this study is that the AMSE, used by non-expert psychiatrists, has sufficiently good diagnostic performance (minimal sensitivity and specificity of respectively 93% and 65%) to be used in screening adults with suspected ASD.

CONDITIONS

Official Title

Validation Study of the Performance of the French Version of the Autism Mental Status Examination Scale as a Tool for Identifying Autism Spectrum Disorder in Adults

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient 18 years of age or older
  • Patient who has requested a diagnostic evaluation at a center specializing in ASD diagnosis
  • Patient covered by national health insurance
Not Eligible

You will not qualify if you...

  • Patient previously diagnosed with Autism Spectrum Disorder by a psychiatrist or child psychiatrist
  • Lack of informed consent from patient or legal guardian
  • Pregnant or breastfeeding
  • Patient deprived of freedom
  • Non-French-speaking patient, parents, or legal guardians
  • AMSE not completed or completed incorrectly by non-expert psychiatrist or psychologist
  • Patient covered by Aide Medicale d'Etat (AME)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pitié-Salpêtrière Hospital

Paris, France

Actively Recruiting

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Research Team

H

Hélène VULSER, MD-PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Validation Study of the Performance of the French Version of the Autism Mental Status Examination Scale as a Tool for Identifying Autism Spectrum Disorder in Adults | DecenTrialz