Actively Recruiting
The Validity of the Quick Renal MRI in Pediatric Kidney Disease
Led by University of Wisconsin, Madison · Updated on 2024-04-03
100
Participants Needed
1
Research Sites
295 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- DMSA) renal scan in the detection of acute renal infections and scars. If the quick renal MRI is accurate, it could potentially replace the DMSA scan for those specific questions and ease the burden of testing for children with chronic renal disease. Findings from these studies will provide preliminary data and rationale for a multi-centered study to further test this new technology. Participants will be 0-21 years of age and can expect to be on study for from 1 week (if enrolled in Aim 1) to 6 months (if enrolled in Aim 2).
CONDITIONS
Official Title
The Validity of the Quick Renal MRI in Pediatric Kidney Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- For Aim 1: Patient is admitted to American Family Children's Hospital for a febrile urinary tract infection, suspected pyelonephritis, or diagnosed pyelonephritis
- For Aim 1: Undergoing clinical DMSA scan
- For Aim 2: Undergoing DMSA scans as part of routine clinical care
- For Aim 2: History of more than one urinary tract infection in the past year
- Age from 0 to 21 years
You will not qualify if you...
- For Aim 1: No evidence of pus cells (pyuria) on urine analysis
- For Aim 1: Negative urine culture
- For Aim 1: Not comfortable with having a Quick MRI performed
- For both aims: Any contraindications to MRI
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
American Family Children's Hospital
Madison, Wisconsin, United States, 53792
Actively Recruiting
Research Team
S
Shannon Cannon, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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