Actively Recruiting
Valproate Versus Propranolol in Migraine
Led by Kafrelsheikh University · Updated on 2024-07-03
600
Participants Needed
1
Research Sites
75 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigators aim to compare the effect of valproate versus propranolol in migraine by assessing the absolute reduction in MMD in each group and the percentage of patients who achieved ≥ 50% reduction in the monthly headache days frequency compared to the baseline frequency.
CONDITIONS
Official Title
Valproate Versus Propranolol in Migraine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Naive migraine patients diagnosed according to the International Classification of Headache Disorders 3rd edition
- Aged between 18 and 75 years
You will not qualify if you...
- Patients with major neurological disorders such as epilepsy, ischemic or hemorrhagic stroke, multiple sclerosis, mitochondrial diseases, brain tumors, or essential tremors
- Patients with major systemic diseases including malignancy, collagen, liver, or renal diseases
- Patients with cardiovascular diseases such as hypertension (systolic >130 or diastolic >85 mm/Hg on at least three occasions), diabetes (fasting glucose >126 mg/dl, casual glucose >200 mg/dl, or HbA1C >6.5)
- Patients with valvular or ischemic heart diseases, bradycardia or heart blocks, congestive heart failure
- Patients who have received prophylactic treatment for migraine
- Patients with contraindications to the study drugs
- Patients with bronchial asthma or chronic obstructive pulmonary disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kafr Elsheikh University Hospital
Kafr ash Shaykh, Egypt, 33511
Actively Recruiting
Research Team
M
mohamed G. Zeinhom, MD
CONTACT
S
sherihan R. ahmed, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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