Actively Recruiting
Valsalva SBP Drop and LVOT Obstruction
Led by Shanghai Zhongshan Hospital · Updated on 2026-03-19
800
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aimed to evaluate the efficacy of non-invasive dynamic blood pressure monitoring in assessing left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy. We prospectively collected SBP waveforms and LVOT gradient data from patients with obstructive and non-obstructive disease, systematically analyzed their correlation, and explored its clinical value in different clinical scenarios.
CONDITIONS
Official Title
Valsalva SBP Drop and LVOT Obstruction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with hypertrophic cardiomyopathy by echocardiography, with or without left ventricular outflow tract obstruction
- Conscious and mentally able to understand and voluntarily sign the informed consent form
- Able to cooperate with provocation tests, non-invasive dynamic hemodynamic monitoring, and follow-up exams
You will not qualify if you...
- Age under 18 years, or pregnant or breastfeeding
- Having other heart or great vessel diseases causing left ventricular outflow tract obstruction, such as severe aortic stenosis or congenital subaortic membrane
- Persistent atrial fibrillation or severe arrhythmias affecting monitoring accuracy
- Previous interventional or surgical treatment for left ventricular outflow tract obstruction, including septal ablation or myectomy
- Considered inappropriate by investigators due to contraindications to provocation tests
- Currently participating in other clinical studies
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhongshan Hospital
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
Z
Ziqing Yu, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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