Actively Recruiting
Value of Analysing Under-utilised Leftover Tissue (VauLT)
Led by Royal Marsden NHS Foundation Trust · Updated on 2025-05-18
800
Participants Needed
1
Research Sites
537 weeks
Total Duration
On this page
Sponsors
R
Royal Marsden NHS Foundation Trust
Lead Sponsor
V
Ventana Medical Systems
Collaborating Sponsor
AI-Summary
What this Trial Is About
Intratumour heterogeneity is well recognized in multiple cancer types and ultimately leads to therapeutic resistance. It also limits the ability of small samples to represent the whole tumour, having implications for diagnosis, molecular analysis and understanding of the tumour immune microenvironment. By blending- 'homogenizing'- leftover tumour tissue in excess of that required for diagnosistic purposes, one may create a more representative sample for analysis.
CONDITIONS
Official Title
Value of Analysing Under-utilised Leftover Tissue (VauLT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Leftover formalin-fixed tissue from cancer surgery that would otherwise be discarded
- Consent provided for use of tissues in research
- Patient age over 18 years
- At least 1 gram of residual tumour present in leftover surgical tissue
- At least 1 gram of normal tissue present
You will not qualify if you...
- Tumour sample deemed inadequate by an advanced practitioner in histological dissection
- Leftover surgical tumour tissue weighs more than 20 kilograms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Royal Marsden Hospital NHS Foundation Trust
London, United Kingdom, SW3 6JJ
Actively Recruiting
Research Team
S
Serena Vanzan
CONTACT
E
Eleanor Carlyle
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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