Actively Recruiting
Value of Biological Age, in Addition to Individual Frailty, for Personalising the Management of Cancer Treated with Targeted Therapy
Led by University Hospital, Clermont-Ferrand · Updated on 2024-09-27
321
Participants Needed
17
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
French prospective multicenter, open-label study involving newly diagnosed CML patients. Two assessments will be performed during the follow-up of these patients: individual frailty using geriatric tools and individual biological aging determined by DNA methylation analysis.
CONDITIONS
Official Title
Value of Biological Age, in Addition to Individual Frailty, for Personalising the Management of Cancer Treated with Targeted Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Chronic phase chronic myeloid leukemia diagnosed no more than 3 months prior to inclusion
- Diagnosis confirmed by Philadelphia chromosome (Ph1) or FISH for cryptic Ph1
- BCR-ABL1 transcript quantifiable by quantitative PCR
- First-line treatment with tyrosine kinase inhibitor
- No prior tyrosine kinase inhibitor or hydroxyurea treatment before first blood sampling
- Signed informed consent for CML Observatory and BIO-TIMER protocol
- Able to read and understand French
- Enrolled in or beneficiary of a social security plan
You will not qualify if you...
- CML in accelerated or blast phase
- Refusal to participate in the study
- Treatment started prior to inclusion
- Under guardianship, curatorship, deprivation of liberty, or safeguard of justice
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 17 locations
1
CHU Annecy-Genevois
Annecy, France
Actively Recruiting
2
Institut Bergonié
Bordeaux, France
Not Yet Recruiting
3
CHU Caen
Caen, France
Actively Recruiting
4
CHU de Clermont-Ferrand
Clermont-Ferrand, France, 63000
Actively Recruiting
5
CHU Créteil
Créteil, France
Not Yet Recruiting
6
CHU Grenoble Alpes
Grenoble, France
Not Yet Recruiting
7
Centre Hospitalier Emile Roux
Le Puy-en-Velay, France
Actively Recruiting
8
CHRU Lille
Lille, France
Not Yet Recruiting
9
CHU Limoges
Limoges, France
Actively Recruiting
10
Centre Léon Bérard
Lyon, France
Withdrawn
11
Institut Paoli-Calmettes
Marseille, France
Actively Recruiting
12
CHU Nancy
Nancy, France
Actively Recruiting
13
Groupe Hospitalier Paris Saclay - Site de Bicêtre
Paris, France
Actively Recruiting
14
CHU Rennes
Rennes, France
Actively Recruiting
15
CHU Saint-Etienne
Saint-Etienne, France
Actively Recruiting
16
Institut Universitaire du Cancer de Toulouse - Oncopole
Toulouse, France
Actively Recruiting
17
CHU Versailles
Versailles, France
Actively Recruiting
Research Team
L
Lise LACLAUTRE
CONTACT
M
Mélanie CASILE, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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