Actively Recruiting
The Value of CEUS in Assessing the Response of Cervical Lymph Nodes After NACI for HNSCC
Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2024-12-10
100
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The head and neck squamous cell carcinoma is the sixth most common malignant tumor worldwide. For patients with locally advanced head and neck cancer, neoadjuvant therapy is recommended before surgery, including neoadjuvant chemotherapy and immunotherapy. There is a significant variation in patients' responses to neoadjuvant therapy, with approximately 37%-52% of patients achieving a complete pathological response after neoadjuvant therapy. Current research mainly focuses on the efficacy evaluation of the primary tumor, while there is less research on the treatment efficacy evaluation of cervical lymph nodes. In clinical practice, accurate assessment of the status of cervical lymph nodes after neoadjuvant chemoimmunotherapy in patients with squamous cell carcinoma of the head and neck can directly affect the choice of treatment plan by clinicians, reducing unnecessary neck dissection. In recent years, contrast-enhanced ultrasound has been widely used in the diagnosis of thyroid cancer and other head and neck tumors, as well as in the assessment of the benign and malignant nature of cervical lymph nodes. This study aims to explore the value of contrast-enhanced ultrasound in the assessment of cervical lymph nodes after neoadjuvant chemoimmunotherapy in squamous cell carcinoma of the head and neck, in order to guide clinicians in formulating personalized treatment plans.
CONDITIONS
Official Title
The Value of CEUS in Assessing the Response of Cervical Lymph Nodes After NACI for HNSCC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathologically confirmed head and neck squamous cell carcinoma
- Received neoadjuvant chemoimmunotherapy
- Diagnosed with cervical lymph node involvement (cN+) by CT or MRI before treatment
- Underwent radical surgical treatment plus cervical lymph node dissection at this center
You will not qualify if you...
- Did not receive a full course of neoadjuvant therapy
- History of prior treatment for head and neck cancer
- Clinical evidence of distant metastasis found during preoperative examination
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, China
Actively Recruiting
Research Team
L
Lin Peiliang, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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