Actively Recruiting
The Value of Molecular Residual Disease Monitoring Based on ctDNA in Resected Pancreatic Cancer
Led by Peking Union Medical College Hospital · Updated on 2023-04-12
100
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to explore the value of molecular residual disease (MRD) monitoring based on ctDNA in resected pancreatic cancer. The main questions it aims to answer are: * prognostic value of baseline MRD; * the role of MRD dynamic changes after treatment in guiding treatment. Peripheral blood derived from participants will be obtained for MRD test before adjuvant chemotherapy initiation and at the first imaging assessment after chemotherapy.
CONDITIONS
Official Title
The Value of Molecular Residual Disease Monitoring Based on ctDNA in Resected Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with pancreatic cancer who have undergone curative-intent surgery (R0 or R1 resection)
- Both sexes, age 18 years or older
- ECOG performance status score of 2 or less
- Expected survival time of 3 months or more
You will not qualify if you...
- Diagnosis of pancreatic cancer other than ductal adenocarcinoma
- Received any systemic antitumor treatment before first-line chemotherapy
- Died or lost to follow-up within one month after starting adjuvant chemotherapy
- Having other primary malignancies
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, China, 100032
Actively Recruiting
Research Team
C
Chunmei Bai, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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