Actively Recruiting

Age: 1Year - 16Years
All Genders
NCT07313514

The Value of the O-RADS Radiological Classification in Predicting the Malignancy of Ovarian Masses in Children

Led by University Hospital, Strasbourg, France · Updated on 2026-01-02

100

Participants Needed

1

Research Sites

46 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

When faced with an ovarian mass in a girl, conservative surgery (resection of the mass while preserving healthy ovarian tissue) via laparoscopy remains the most appropriate treatment option. However, this option is no longer indicated for malignant tumors, as this presents a risk of tumor dissemination that can significantly alter the child's subsequent prognosis. Therefore, for any malignant or suspected malignant tumor, radical treatment consisting of oophorectomy or salpingo-oophorectomy, often via laparotomy, is the standard. While keeping this therapeutic principle in mind, differentiating between benign and malignant entities remains the major challenge for clinicians. Furthermore, the diagnostic accuracy of the O-RADS classification based on MRI is not sufficiently established in the literature for children. Our project aims to conduct a multicenter study in the pediatric population to investigate the usefulness of this radiological classification in the preoperative diagnosis of ovarian masses.

CONDITIONS

Official Title

The Value of the O-RADS Radiological Classification in Predicting the Malignancy of Ovarian Masses in Children

Who Can Participate

Age: 1Year - 16Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Girls under 16 years of age
  • Girls who underwent surgery for ovarian masses at the Pediatric Surgery Department of Mohammed VI University Hospital in Oujda during the study period
  • Girls who underwent surgery for ovarian masses at the Pediatric Surgery Department of Strasbourg University Hospital during the study period
  • Girls who underwent preoperative MRI
Not Eligible

You will not qualify if you...

  • Girls who underwent preoperative MRI
  • Patients who did not undergo surgery
  • Patients without histopathological examination of the surgical specimen
  • Patients without MRI as a preoperative diagnostic evaluation modality

AI-Screening

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Trial Site Locations

Total: 1 location

1

Service de Chirurgie Pédiatrique - CHU de Strasbourg - France

Strasbourg, France, 67091

Actively Recruiting

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Research Team

I

Isabelle TALON, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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