Actively Recruiting
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
Led by Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · Updated on 2026-03-24
310
Participants Needed
7
Research Sites
346 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between echocardiography and catheterization, with an overestimation of the real gradient with echo (vs. cath) in most cases. Thus, the incidence of procedural-device failure may be lower than that reported in the ViV-TAVR literature,
CONDITIONS
Official Title
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with surgical aortic bioprosthetic valve failure defined as severe aortic stenosis and/or regurgitation approved for a valve-in-valve procedure by the Heart Team
- Surgical stented bioprosthetic valve with a labeled size of 25 mm or less
- Undergoing TAVR with the SAPIEN 3 Ultra valve
You will not qualify if you...
- Stentless or sutureless surgical valves
- Trifecta bioprosthesis
- Hancock II bioprosthesis
- High risk of coronary obstruction defined by a virtual transcatheter valve to coronary distance less than 4 mm on CT or by Heart Team assessment
- Inability to provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
University of California
San Francisco, California, United States, 94143
Not Yet Recruiting
2
South Broward Hospital Disctrict D/B/A Memorial Healthcare System
Hollywood, Florida, United States, 33021
Actively Recruiting
3
William Beaumont Hospital
Royal Oak, Michigan, United States, 48073
Actively Recruiting
4
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
5
St-Joseph's Health INC
Syracuse, New York, United States, 13203
Not Yet Recruiting
6
The Christ Hospital Health Network
Cincinnati, Ohio, United States, 45219
Actively Recruiting
7
IUCPQ
Québec, Quebec, Canada, G1V 4G5
Actively Recruiting
Research Team
J
Josep Rodés-Cabau, MD
CONTACT
E
Emilie Pelletier Beaumont, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here