Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06772675

Vancomycin Reduction Practices (VRP) in the NICU

Led by Children's Hospital of Philadelphia · Updated on 2025-12-24

13

Participants Needed

13

Research Sites

117 weeks

Total Duration

On this page

Sponsors

C

Children's Hospital of Philadelphia

Lead Sponsor

A

Agency for Healthcare Research and Quality (AHRQ)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.

CONDITIONS

Official Title

Vancomycin Reduction Practices (VRP) in the NICU

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • NICU is a Level III neonatal intensive care unit
  • NICU is affiliated with Kaiser Permanente Northern California or Children's Hospital of Philadelphia Newborn Care Network
  • NICU has been recruited by the study team
Not Eligible

You will not qualify if you...

  • NICU site has not been recruited for the study

AI-Screening

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Trial Site Locations

Total: 13 locations

1

Kaiser Permanente Modesto Medical Center

Modesto, California, United States, 95356

Actively Recruiting

2

Kaiser Permanente East Bay - Oakland Medical Center

Oakland, California, United States, 94611

Actively Recruiting

3

Kaiser Permanente Roseville Medical Center

Roseville, California, United States, 95661

Actively Recruiting

4

Kaiser Permanente San Francisco Medical Center

San Francisco, California, United States, 94115

Actively Recruiting

5

Kaiser Permanente San Leandro Medical Center

San Leandro, California, United States, 94577

Actively Recruiting

6

Kaiser Permanente Santa Clara Medical Center

Santa Clara, California, United States, 95051

Actively Recruiting

7

Kaiser Permanente Walnut Creek Medical Center

Walnut Creek, California, United States, 94596

Actively Recruiting

8

Medical Center of Princeton

Plainsboro, New Jersey, United States, 08536

Actively Recruiting

9

Virtua Voorhees

Voorhees Township, New Jersey, United States, 08043

Actively Recruiting

10

Lancaster General Hospital

Lancaster, Pennsylvania, United States, 17602

Actively Recruiting

11

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

12

Pennsylvania Hospital

Philadelphia, Pennsylvania, United States, 19107

Actively Recruiting

13

Chester County Hospital

West Chester, Pennsylvania, United States, 19380

Actively Recruiting

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Research Team

K

Kayla Gilpin

CONTACT

M

Morgan Gabbert

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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