Actively Recruiting
Vaping and Smoking Withdrawal Project
Led by State University of New York at Buffalo · Updated on 2026-03-09
370
Participants Needed
1
Research Sites
197 weeks
Total Duration
On this page
Sponsors
S
State University of New York at Buffalo
Lead Sponsor
R
Roswell Park Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed research, which will systematically and comprehensively characterize the withdrawal among daily vapers compared to daily smokers of combustible cigarettes, filling critical gaps in the understanding of electronic nicotine delivery systems (ENDS) dependence/abuse liability and contributing to the development of therapies for tobacco/nicotine use, the leading preventable cause of death in the US.
CONDITIONS
Official Title
Vaping and Smoking Withdrawal Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Daily or near-daily nicotine vaping and/or cigarette smoking for 6 months or longer
- Cotinine level of 200+ ng/mL on a quick commercial test
You will not qualify if you...
- Planning to quit daily or near-daily vaping or smoking within the next month
- Using pipe tobacco, hookah/shisha, smokeless tobacco, dissolvable tobacco, or nicotine pouches 2+ days in the past 7 days
- For vapers only, using cigars, cigarillos, or filtered cigars filled with tobacco or tobacco and marijuana 2+ days in the past 7 days
- Current use of any smoking cessation medication
- Severe substance dependence other than tobacco/nicotine (including cannabis) as indicated by NIDA Modified ASSIST score of 27 or higher
- Suicidal thoughts with intent or plan in the past 2 weeks
- Taking antipsychotic medications currently or having a history of schizophrenia or bipolar disorder
- Pregnancy as determined by urine test at intake
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University at Buffalo
Buffalo, New York, United States, 14260
Actively Recruiting
Research Team
L
Larry Hawk, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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