Actively Recruiting
Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors
Led by Central Hospital, Nancy, France · Updated on 2026-02-25
90
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Microwave ablation is a minimally invasive technique whose planning relies on manufacturer tables derived from ex vivo models that do not account for patient or tumor-specific factors. In clinical practice, the actual ablation volume often differs from the planned volume due to liver characteristics, vascular proximity, and tumor biology. This study aims to assess the variability between ablation small axis during percutaneous microwave ablation of liver lesions. The influence of patient-related (fibrosis, steatosis, portal flow) and tumor-related factors (location, histology, prior treatment) will be evaluated. Small axis and volume will be compared with volumes measured on immediate post-procedural CT and on CT/MRI at 6-12 weeks, accounting for expected tissue shrinkage.
CONDITIONS
Official Title
Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients
- Treated with percutaneous hepatic microwave ablation under CT or ultrasound guidance
- Adult treated for one or more liver lesions
- Patients with available follow-up imaging
You will not qualify if you...
- Two treatment cycles on the same lesion during the same session
- Reoperation on the same lesion
- Planned volume not available (no manufacturer data, not specified in the surgical report)
- No control imaging injected between 1 and 4 months post-procedure
- Final ablation volume not measurable (e.g., artifacts, no injection on MRI)
- No definitive diagnosis of the nature of the tumor on imaging and no histology available
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CHRU Nancy
Vandœuvre-lès-Nancy, France, F54511
Actively Recruiting
Research Team
V
Valérie LAURENT, MD-PhD
CONTACT
A
Astrée LEMORE, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here