Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT04828954

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb

Led by University of Chicago · Updated on 2026-05-13

90

Participants Needed

1

Research Sites

328 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the optimal duration of postoperative immobilization. Immobilization following surgery is critical for wound healing, pain control, and aid with activities of daily living in the early recovery period, though the duration of this must be weighed against the negative impacts of immobilization, such as stiffness, contracture, and delay in return to full function. The information gained in this study may allow hand surgeons to use an evidence-based postoperative rehabilitation protocol. Thus, our goal is to compare varying durations of postoperative immobilization after thumb CMC arthroplasty in a randomized trial design. Subjects will be randomized to treatment with non-removable thumb spica plaster postoperative splint immobilization for 2 weeks or non-removable thumb spica plaster splint transitioned to cast for a total of 6 weeks immobilization following base of thumb arthroplasty. Patient-reported outcome measures (PROs) and objective metrics will be tracked in the follow-up period.

CONDITIONS

Official Title

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 40 years or older
  • Patients undergoing arthroplasty of the first carpometacarpal joint including trapeziectomy with ligament reconstruction and tendon interposition (LRTI)
  • Patients undergoing simple trapeziectomy
  • Patients undergoing suspensionplasty (suture vs. abductor pollicis longus)
Not Eligible

You will not qualify if you...

  • Patients younger than 40 years
  • Patients with prior surgical procedures on the base of the thumb
  • Patients planning or having had concomitant carpal tunnel release or thumb metacarpophalangeal arthrodesis
  • Patients undergoing implant arthroplasty
  • Patients diagnosed with inflammatory arthritis
  • Patients diagnosed with hypermobility syndrome

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University of Chicago Medicine

Chicago, Illinois, United States, 60637

Actively Recruiting

Loading map...

Research Team

A

Andrew Straszewski, MD

CONTACT

J

Justin Bell

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb | DecenTrialz