Actively Recruiting
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Led by University of Chicago · Updated on 2026-05-13
90
Participants Needed
1
Research Sites
328 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the optimal duration of postoperative immobilization. Immobilization following surgery is critical for wound healing, pain control, and aid with activities of daily living in the early recovery period, though the duration of this must be weighed against the negative impacts of immobilization, such as stiffness, contracture, and delay in return to full function. The information gained in this study may allow hand surgeons to use an evidence-based postoperative rehabilitation protocol. Thus, our goal is to compare varying durations of postoperative immobilization after thumb CMC arthroplasty in a randomized trial design. Subjects will be randomized to treatment with non-removable thumb spica plaster postoperative splint immobilization for 2 weeks or non-removable thumb spica plaster splint transitioned to cast for a total of 6 weeks immobilization following base of thumb arthroplasty. Patient-reported outcome measures (PROs) and objective metrics will be tracked in the follow-up period.
CONDITIONS
Official Title
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 40 years or older
- Patients undergoing arthroplasty of the first carpometacarpal joint including trapeziectomy with ligament reconstruction and tendon interposition (LRTI)
- Patients undergoing simple trapeziectomy
- Patients undergoing suspensionplasty (suture vs. abductor pollicis longus)
You will not qualify if you...
- Patients younger than 40 years
- Patients with prior surgical procedures on the base of the thumb
- Patients planning or having had concomitant carpal tunnel release or thumb metacarpophalangeal arthrodesis
- Patients undergoing implant arthroplasty
- Patients diagnosed with inflammatory arthritis
- Patients diagnosed with hypermobility syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Chicago Medicine
Chicago, Illinois, United States, 60637
Actively Recruiting
Research Team
A
Andrew Straszewski, MD
CONTACT
J
Justin Bell
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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