Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
NCT05727930

Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2)

Led by Indiana University · Updated on 2026-03-27

100

Participants Needed

1

Research Sites

300 weeks

Total Duration

On this page

Sponsors

I

Indiana University

Lead Sponsor

N

Northwestern University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed research will evaluate the individual and combined effects of task-specificity and intensity of rehabilitation interventions on locomotor function, community mobility and quality of life in patients with subacute (1-6 months) post-stroke.

CONDITIONS

Official Title

Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2)

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Sub-acute stroke between 1 and 6 months
  • Hemiparesis with Fugl-Meyer score below 34 and no cerebellar deficits
  • Ability to walk 10 meters with or without assistance but slower than 1.0 m/s; assistive devices and below-knee bracing allowed
  • Ability to sit unsupported for over 30 seconds
  • Ability to follow 3-step commands
  • Provide informed consent and have medical clearance to participate
  • Must be able to consent or have a legal representative provide consent
Not Eligible

You will not qualify if you...

  • Significant cardiovascular, metabolic, or respiratory diseases limiting exercise (including recent heart attack, heart failure, high blood pressure, uncontrolled diabetes, advanced kidney disease, serious infections, psychiatric illness, or cancer)
  • Presence of absolute criteria requiring exercise test termination during treadmill evaluation (e.g., moderate to severe chest pain, certain heart changes)
  • Orthopedic or neurological disorders limiting walking to less than 50 meters before stroke
  • Receiving physical therapy at baseline testing
  • Prescribed botulinum toxin doses over 50 units in leg muscles above the knee; if doses over 50 units are below the knee, must use ankle-foot orthosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Rehabilitation Hospital of Indiana

Indianapolis, Indiana, United States, 46254

Actively Recruiting

Loading map...

Research Team

G

George Hornby

CONTACT

C

Chris Henderson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

4

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here