Vascular Changes Associated With Endophthalmitis

What this Trial Is About

Researchers are investigating vascular changes linked to exogenous endophthalmitis, a serious eye infection, by using detailed imaging techniques. This observational study aims to better understand how blood vessels change during the infection and recovery phases. It also plans to create a photo library to document these vascular changes, helping to distinguish effects caused by immune response, drug toxicity, or reduced blood flow. The study is conducted at the Asociacif3n para Evitar la Ceguera en Me9xico and involves patients with a history of endophthalmitis who meet specific resolution criteria. The study uses multimodal imaging including fundus photography, optical coherence tomography, and fluorescein angiography to examine the eyes. These tests are performed twice: once seven days and again one month after patients meet the infection inactivation criteria set by the Mexican Endophthalmitis Study Group. This approach allows researchers to monitor and characterize vascular changes over time without administering any treatment, as this is an observational study. Participants will undergo clinical evaluations including visual acuity tests at each visit scheduled at seven days and one month post-inactivation. Imaging procedures will be repeated at these visits to capture detailed vascular changes. Researchers will collect comprehensive clinical data including medical histories, eye examinations, and laboratory results. The study emphasizes careful monitoring and documentation to improve understanding of endophthalmitis outcomes. Participation duration varies based on individual recovery timelines, with no investigational treatments applied.

Vascular Changes Associated With Endophthalmitis.