Actively Recruiting
Vascular Complications After Kidney Transplantation
Led by University of Aarhus · Updated on 2026-04-15
60
Participants Needed
3
Research Sites
260 weeks
Total Duration
On this page
Sponsors
U
University of Aarhus
Lead Sponsor
A
Aarhus University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
* To determine the incidence of arterial inflow problems and venous outflow problems as causes of impaired renal function and/or treatment-resistant hypertension after kidney transplantation, when all kidney-transplant recipients in Denmark are evaluated according to uniform, well-defined clinical criteria. * To investigate the efficacy and safety of catheter-based balloon treatment (percutaneous transluminal angioplasty, PTA) for these vascular complications, of which transplant renal artery stenosis is by far the most common. * To assess whether novel imaging and functional diagnostic methods can predict treatment response.
CONDITIONS
Official Title
Vascular Complications After Kidney Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have impaired kidney function after transplant, defined by acute drop in kidney filtration rate, low filtration rate 30 days post-transplant, or decline after certain blood pressure medications
- Have persistent resistant hypertension for more than 6 weeks after transplant despite treatment with at least three types of blood pressure medications
- Show at least one radiological sign of artery narrowing by CT, MR angiography, or Doppler ultrasound
- Confirmed stenosis of 70% or more, or 50-69% with specific pressure gradient criteria
- Able to provide informed consent
You will not qualify if you...
- Unable to give informed consent
- Have active rejection of the kidney transplant requiring treatment
- Pregnant
- Have had balloon angioplasty (PTA) on the same vessel before
- Cannot tolerate any blood clot prevention therapy and so cannot receive stents
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Aarhus University Hospital
Aarhus, Denmark, 8200
Actively Recruiting
2
Rigshospitalet
Copenhagen, Denmark, 2100
Actively Recruiting
3
Odense University Hospital
Odense, Denmark, 5000
Actively Recruiting
Research Team
M
Mark Reinhard, MD, PhD
CONTACT
H
Henrik Birn, MD, DMSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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