VALIANCE Study Tracking Heart and Other Risks After Elective Same-day Noncardiac Surgery in Adults

What this Trial Is About

Researchers are studying the risks and outcomes of patients undergoing elective same-day noncardiac surgeries, focusing on major cardiovascular and other complications within 90 days after surgery. This large observational study aims to better understand how often these events occur, what factors increase risk, and to develop tools that help predict patient outcomes after same-day surgery. The study will also assess changes in quality of life and validate several questionnaires used to measure physical function and frailty in this context. The study follows 15,000 adults undergoing elective same-day noncardiac surgery lasting at least 60 minutes. These patients will be observed without receiving experimental treatments, allowing researchers to collect real-world data on postoperative complications such as heart attacks, strokes, infections, bleeding, and kidney injury. Quality of life and physical function will be evaluated using validated questionnaires like the EQ-5D-5L and Duke Activity Status Index. Pain will also be assessed using the Brief Pain Inventory score. Participants will be followed for 90 days after surgery through medical record reviews and questionnaires to capture unplanned healthcare visits, cardiovascular events, and other adverse outcomes. The study will measure functional capacity, frailty, and quality of life changes during this time. The main outcome is unplanned healthcare use within 90 days, including hospital admissions and emergency visits. This observational approach helps identify risk factors and improve patient selection and care planning for same-day surgeries.

Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study