Actively Recruiting
Vascular Trial Associated Registry Pilot
Led by Corewell Health West · Updated on 2026-04-13
350
Participants Needed
2
Research Sites
158 weeks
Total Duration
On this page
Sponsors
C
Corewell Health West
Lead Sponsor
H
Henry Ford Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this investigator-initiated, multicenter, open label, randomized trial is to evaluate 1 month vs. 6 months of dual antiplatelet therapy (DAPT) in patients undergoing lower extremity endovascular revascularization. We hypothesize that extending dual antiplatelet therapy (DAPT) to six months, compared to one month, will improve patency rates of target vessels following peripheral vascular intervention (PVI) without significantly increasing complications, particularly bleeding events.
CONDITIONS
Official Title
Vascular Trial Associated Registry Pilot
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than or equal to 45 at time of enrollment
- Patient is scheduled for a peripheral vascular intervention (PVI) or has had one in the last 30 days
- Patient data is being submitted to Fivos, the data collection subcontractor for the VQI-PVI registry
- Diagnosis of atherosclerotic vascular disease
You will not qualify if you...
- Patients who cannot consent for themselves
- Allergy to clopidogrel
- Patients unable to stop clopidogrel for other medical reasons
- Patients on dual pathway inhibition with low dose rivaroxaban (2.5 mg twice a day) who cannot stop these medications
- Allergy to aspirin
- Nonatherosclerotic vascular disease
- Patients undergoing open bypass surgery at the same time as the peripheral angioplasty
- Patients with high bleeding risk, including history of major bleeding, active bleeding disorders, severe kidney impairment (creatinine clearance <30), concurrent anticoagulation, or platelet count below 100,000
- Recent stroke within 6 months
- Current therapy with warfarin or full-dose direct oral anticoagulants
- Patients unwilling or unable to comply with standard follow-up visits
- Pregnant women
- Prisoners
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Henry Ford Hospital
Detroit, Michigan, United States, 48202-2608
Not Yet Recruiting
2
Corewell Health West
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
Research Team
S
Stephen C Orey, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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