Actively Recruiting
Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia
Led by University of Aarhus · Updated on 2026-03-19
32
Participants Needed
1
Research Sites
210 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The optimal vasopressor for ensuring organ blood flow and tissue oxygen delivery during surgery remains undetermined. This study aim to compare the effects of noradrenaline vs. phenylephrine infusion on blood flow and oxygen delivery to the brain and various other organs in anesthetized neurosurgical patients.
CONDITIONS
Official Title
Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of supratentorial malignant or non-malignant brain tumors, preferably 3 cm or larger
- Scheduled for elective supratentorial craniotomy
- Aged between 18 and 75 years
- American Society of Anesthesiologists status 1-3
You will not qualify if you...
- Allergy or intolerance to noradrenaline or phenylephrine
- Active treatment with monoamine oxidase inhibitors
- American Society of Anesthesiologists physical status IV-VI
- Pregnancy or breastfeeding
- Unable to provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Aarhus University Hospital
Aarhus, Denmark, 8200
Actively Recruiting
Research Team
R
Rasmussen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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