Effects of Velocity-Based Resistance Training on Renal Function and Metabolic Health in Kidney Transplant Recipients: Protocol for a Randomized Controlled Trial

What this Trial Is About

Researchers are evaluating the effects of velocity-based resistance training on kidney function and metabolic health in adults who have received a kidney transplant. This randomized controlled trial will compare two groups performing resistance exercises at different speeds to understand how these training methods influence renal and metabolic outcomes. The study focuses on kidney transplant recipients who are stable and medically cleared for exercise. Participants will be randomly assigned to one of two groups for a 12-week supervised resistance training program, with sessions three times per week. One group will perform exercises like squat, bench press, and military press at maximal intended speed, stopping sets when movement speed drops by 20%. The other group will perform the same exercises at about half of their maximal speed, completing a set number of repetitions. Training loads will increase progressively from 20% to 60% of their one-repetition maximum, and a Smith machine with a linear encoder will be used to monitor velocity. During the study, participants will be evaluated at the start and after the 12-week training period. Researchers will measure kidney function markers such as serum creatinine, estimated glomerular filtration rate, blood urea nitrogen, and uric acid, along with metabolic health indicators like cholesterol, triglycerides, glucose, waist size, and blood pressure. Secondary assessments include muscle strength, body composition, physical activity levels, fitness perception, and adherence to immunosuppressive medication. Safety and health will be closely monitored throughout the trial, which is expected to last until the end of 2027.

Velocity-Based Resistance Training in Kidney Transplant Recipients