Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.
Luis A Garza, Yaping Liu, Zaixin Yang...
https://pubmed.ncbi.nlm.nih.gov/22440736/Actively Recruiting
Led by Institute of Dermatology, Thailand · Updated on 2026-05-13
80
Participants Needed
2
Research Sites
N/A
Total Duration
Researchers are evaluating the effectiveness and tolerability of a peptide-based hair serum compared with topical minoxidil in adults with androgenetic alopecia pattern hair loss. This condition affects both men and women and can impact quality of life. The study aims to measure improvement in hair growth, including changes in hair density and thickness, while also assessing safety and patient-reported outcomes. Participants will be randomly assigned in a double-blind manner to apply either the VENEZE peptide factor hair serum or a 2% minoxidil solution topically to the scalp twice daily for 24 weeks. Both treatments are administered according to the study protocol. The study includes two groups one using the peptide serum and the other using minoxidil as an active comparator. During the study, participants will attend scheduled visits where researchers will measure hair density, hair thickness, and terminal hair count at 12 and 24 weeks. Additional assessments include the Investigator Global Aesthetic Improvement Scale, androgenetic alopecia severity, patient global assessments, and monitoring for any adverse events. Participants are expected to maintain consistent hair color and hairstyle and attend all visits throughout the 24-week treatment period.
CONDITIONS
VENEZE Peptide Factor Hair Serum Compared With Topical 2% Minoxidil for Androgenetic Alopecia
C
Chinmanat Lekhavat, MD, PhD
S
Suchanaree Laitrakul, MD
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Institute of Dermatology, Thailand
Lead Sponsor
MEDEZE Cosmeceutical Company Limited
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 24 weeks
Participants apply either the VENEZE peptide factor hair serum or topical 2% minoxidil solution to the scalp twice daily as per the study protocol to treat androgenetic alopecia.
Regular visits during the 24-week treatment period as per study protocol
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Lead Sponsor
MEDEZE Cosmeceutical Company Limited
Collaborating Sponsor