Study of Venous Congestion During Cardiac Surgery and Its Link to Acute Kidney Injury

What this Trial Is About

Researchers are studying the role of venous pressure during cardiac surgery and its connection to cardiac surgery-associated acute kidney injury CSA-AKI. Elevated venous pressure and blood stasis can cause swelling in organ tissues, potentially leading to complications like acute kidney injury. This prospective cohort study aims to identify if intraoperative systemic venous congestion is linked to postoperative CSA-AKI and other complications, seeking a physiological marker to help predict the risk. The study involves adult patients scheduled for elective cardiac surgery. Researchers will collect various data including patient demographics, medical history, surgery-related parameters, kidney function, biological laboratory markers, hemodynamic measurements, and echocardiographic and venous ultrasound assessments. These evaluations will help understand how venous congestion during surgery relates to outcomes. The study does not involve experimental treatments but observes and records these parameters throughout the surgical and postoperative periods. Participants will undergo assessments before, during, and after surgery, including ultrasound scans of the heart and veins, blood tests for kidney function and inflammation markers, and monitoring of heart and blood pressure parameters. Researchers will track postoperative complications, kidney injury occurrences, and other clinical outcomes for up to one year. The primary outcome is acute kidney injury defined by specific changes in serum creatinine within 7 days after surgery. This comprehensive monitoring aims to clarify how venous congestion during surgery affects recovery and long-term health.

Venous Congestion and Cardiac Surgery-Associated Acute Kidney Injury