Actively Recruiting
Study of Venous Congestion and Delirium After Heart Surgery in Adults
Led by Zhuan Zhang · Updated on 2025-12-23
120
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the connection between intraoperative systemic venous congestion and postoperative delirium POD in adults undergoing cardiac surgery. POD is a common complication after heart surgery, marked by confusion, inattention, and cognitive problems, affecting up to 52% of patients. The study also explores how venous congestion relates to other post-surgery complications and brain function disturbances due to altered blood flow and pressure. This prospective cohort study involves adult patients scheduled for elective cardiac surgery using a midline thoracic incision. Researchers will collect various data including patient demographics, medical history, surgery details, and intraoperative factors. They will perform neurological assessments for delirium during the first 7 days after surgery. The study includes detailed monitoring of biological markers, hemodynamic parameters, echocardiographic and venous ultrasound measurements, and central nervous system monitoring such as brain oxygen levels and wave patterns. Participants will undergo multiple evaluations including cognitive tests, ultrasound scans of veins and heart function, laboratory blood tests, and monitoring of vital signs and brain activity. Researchers will track postoperative delirium and other complications up to 30 days after surgery, with follow-up extending to one year. The main outcome measured is the occurrence of delirium within 7 days post-surgery. The study aims to understand how venous congestion during surgery may impact brain function and recovery after cardiac procedures.
CONDITIONS
Brief Title
Venous Congestion And Delirium After Cardiac Surgery
Research Team
Z
Zhuan Zhang, MD
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