Actively Recruiting
Ventilation and Perfusion in Asthmatics
Led by University of Miami · Updated on 2026-05-05
40
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
Sponsors
U
University of Miami
Lead Sponsor
A
Australian Lung Health Initiative Pty Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
Assess regional changes to perfusion and ventilation from inhaled corticosteroid (ICS) and Fast-acting beta-antagonist (FABA) among adult asthmatics using radiographically derived estimates of regional ventilation (V-distribution), ventilation defect percentage (VDP), and ventilation heterogeneity (VH).
CONDITIONS
Official Title
Ventilation and Perfusion in Asthmatics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Physician diagnosis of asthma
- Baseline Forced Expiratory Volume in 1 Second (FEV1) < 80% of predicted with at least 10% reversibility after bronchodilator
- Adults between 18 and 75 years old
- Using a stable dose of inhaled corticosteroids for at least 3 months before enrollment
You will not qualify if you...
- Current cigarette smoking or history of more than 10 pack-years
- Current use of nicotine vaping
- Pregnant or breastfeeding women
- Respiratory infection within 4 weeks before study
- Forced Expiratory Volume in 1 Second (FEV1) less than 50%
- Intolerance to inhaled corticosteroids or fast-acting beta agonists
- Use of beta-blocker medications
- Use of systemic glucocorticosteroids or oral methyl-xanthines within 30 days before study visit
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Miami - Converge Miami
Miami, Florida, United States, 33136
Actively Recruiting
Research Team
M
Maria McCoy
CONTACT
S
Sonia Dipti Meena Velmurugan, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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