Actively Recruiting
Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens
Led by CHU de Reims · Updated on 2025-06-17
265
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ventilator-associated pneumonia (VAP) remains one of the main nosocomial infections acquired in the intensive care unit (ICU). VAP is pneumonia occurring 48 hours after intubation. Today, bronchoalveolar lavage (BAL) is used for microbiological diagnosis, with bacterial culture and antibiotic susceptibility results within 48 to 72 hours. Multiplex PCR can detect DNA of a number of bacteriae, as well as the presence of resistance genes. However, its clinical value in the ICU remains to be demonstrated. We think that the use of multiplex PCR with a panel adapted to the microbiology of VAP, could be an interesting method for clinicians in ICU.
CONDITIONS
Official Title
Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients hospitalized in intensive care units
- On mechanical ventilation for at least 48 hours
- Suspected ventilator-associated pneumonia
- Indication for bronchoalveolar lavage (BAL) procedure
You will not qualify if you...
- Patients under legal protection or without social security coverage
- Pregnant women
- Previous episode of ventilator-associated pneumonia during the same hospitalization
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Damien JOLLY
Reims, France
Actively Recruiting
Research Team
A
Antoine GOURY
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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