Actively Recruiting
Ventilatory Parameters in Acute Neurological Injury
Led by Ramos Mejía Hospital · Updated on 2026-03-30
19
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to test the association between baseline ventilatory parameters (in particular mechanical power (MP), mechanical power normalized to predicted body weight (MP/PBW) and driving pressure (DP) with the baseline neurological status (assessed through the Glasgow coma score) in adults patients under mechanical ventilation with acute neurological injury secondary to stroke, brain trauma or subarachnoid hemorrhage. The main question\[s\]it aims to answer are: 1. In patients with acute neurological injury under mechanical ventilation, is there a correlation between the acute neurological injury, assessed using the Glasgow scale on admission, and baseline ventilatory parameters? 2. In patients with acute neurological injury under mechanical ventilation, are the baseline ventilatory parameters altered at baseline?
CONDITIONS
Official Title
Ventilatory Parameters in Acute Neurological Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute neurological injury in patients 16 years of age or older
- Requiring mechanical ventilation for neurological causes
- No baseline lung injury, defined as normal chest x-ray and adequate oxygenation
- PaO2/FiO2 ratio of 300 or greater
- Use of Neumovent TS and Neumovent Advance respirators
You will not qualify if you...
- Pneumothorax or presence of a pleural drainage tube
- Hemodynamic instability with mean blood pressure 65 mmHg or lower
- Use of high doses of inotropes (Norepinephrine greater than 0.5 gammas/kilo/minute or equivalent)
- PaO2/FiO2 ratio less than 80 mmHg
- Chronic obstructive pulmonary disease (COPD)
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Roberto Santa Cruz
Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, B6600KCL
Actively Recruiting
Research Team
R
Roberto S Santa Cruz, Dr.
CONTACT
A
Antonella Civile, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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