Actively Recruiting
Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease
Led by Children's Hospital Medical Center, Cincinnati · Updated on 2026-01-21
130
Participants Needed
3
Research Sites
198 weeks
Total Duration
On this page
Sponsors
C
Children's Hospital Medical Center, Cincinnati
Lead Sponsor
T
Thrasher Research Fund
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to learn if infants with sickle cell disease (SCD) develop adequate protection after measles vaccines. (not looking at any prolonged duration)
CONDITIONS
Official Title
Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants with confirmed Sickle Cell Disease.
- Children aged between 6 months and 6 years who are due for measles vaccination within 3 months according to national guidelines.
- Willing and able to provide informed consent.
- Able to comply with study evaluations and follow-up visits.
You will not qualify if you...
- Known primary immunodeficiency syndrome, cancer, or acquired immunodeficiency syndrome (AIDS) that prevents vaccination with live virus vaccines.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
Actively Recruiting
2
Korle Bu Teaching Hospital
Accra, Ghana, Ghana
Actively Recruiting
3
Bugando Medical Centre
Mwanza, Tanzania
Actively Recruiting
Research Team
T
Teresa Latham
CONTACT
A
Amy Shova
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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