Comparing Connective Tissue Graft and Dermal Matrix with Enamel Matrix Derivative for Soft Tissue Repair Around Dental Implants

What this Trial Is About

This clinical trial investigates two different methods for vertical soft tissue augmentation at dental implant sites that have soft tissue dehiscences. The study compares the use of autogenous connective tissue grafts taken from the patients palate versus a combination of acellular dermal matrix and enamel matrix derivative. Researchers will evaluate clinical results, tissue volume, ultrasound measurements, and patient feedback over the course of one year. Participants will receive either a connective tissue graft harvested and prepared as a free gingival graft or treatment using acellular dermal matrix combined with enamel matrix derivative. These procedures aim to improve the soft tissue around dental implants in the esthetic zone affected by soft tissue loss. The trial is randomized with single masking to compare outcomes between the two groups. During the study, participants will undergo assessments at multiple time points up to 12 months, including measurements of soft tissue dehiscence depth, mucosal thickness, and 3D volumetric changes. Patient-reported pain will be recorded 14 days after surgery, and professional esthetic evaluations will be performed at 12 months. The primary outcome focuses on changes in soft tissue dehiscence depth after one year of treatment.

Vertical Soft Tissue Augmentation With CTG vs ADM