Actively Recruiting

Phase Not Applicable
Age: 8Years +
All Genders
NCT04067596

Very Large Sizes in Adolescents : Tibial and Femoral EPIphysiodesis

Led by Centre Hospitalier Intercommunal Creteil · Updated on 2023-09-06

20

Participants Needed

3

Research Sites

340 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The very large sizes can be very disabling and at the origin of a difficult psychological experience. Some families are in demand for a growth-curbing treatment. Currently, only hormonal treatments are offered in France but they are at the origin of many side effects. Northern European countries applied a surgical technique, deviated from the one used for a long time in leg asymmetries, to sterilize the proximal tibial and distal femoral growth cartilage, with most of the growth taking place at this level. The goal of this project is to be able to offer this technique to families in demand.

CONDITIONS

Official Title

Very Large Sizes in Adolescents : Tibial and Femoral EPIphysiodesis

Who Can Participate

Age: 8Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescent consulting for very large size with a request for growth inhibition
  • Very large idiopathic or secondary height with no other possible etiological treatment
  • Tanner score of at least 3 for boys and at least 2 for girls
  • Age at onset (A0) less than or equal to 14 years for boys and less than or equal to 12.5 years for girls
  • Chronological age between 10 and 16 years for boys and between 8 and 14 years for girls
  • Actual height at least 167.5 cm at 10 years old to at least 180 cm at 16 years old for boys and at least 160 cm at 8 years old to at least 174 cm at 14 years old for girls
  • Predicted height of at least 198 cm for boys and at least 184 cm for girls
  • Radiological persistence of tibial and femoral growth cartilage with estimated residual growth of at least 8 cm
  • No psychological contraindication to growth-curbing treatment
  • Agreement of parents and adolescent for epiphysiodesis surgery
  • Agreement of parents and adolescent to participate in the study
  • Affiliated to a social security scheme
Not Eligible

You will not qualify if you...

  • Very large size caused by a medically treatable condition such as acromegaly
  • Refusal by parents or adolescent for epiphysiodesis surgery
  • Refusal by parents or adolescent to participate in the study
  • Medical or psychological contraindication to surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

CHI Creteil

Créteil, France, 94000

Actively Recruiting

2

Pôle médical de Sénart

Lieusaint, France

Actively Recruiting

3

Hôpital privé Claude Galien

Quincy-sous-Sénart, France

Actively Recruiting

Loading map...

Research Team

C

Camille JUNG, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here