Actively Recruiting
Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy
Led by Summit Hyperbarics and Wellness · Updated on 2025-10-09
54
Participants Needed
1
Research Sites
49 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate how hyperbaric oxygen therapy (HBOT) may affect cognitive functioning, post-traumatic stress disorder (PTSD), depression, anxiety, and overall quality of life in veterans. 1. Does Hyperbaric Oxygen Therapy improve cognitive functioning, psychological well-being, and quality of life among veterans, as measured by pre-and post-treatment scores? 2. To what extent does Hyperbaric Oxygen Therapy improve cognitive functioning, psychological well-being, and qualify of life among veterans, after controlling for demographic characteristics.
CONDITIONS
Official Title
Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years of age
- Veteran status
- Clinically diagnosed with mild traumatic brain injury, PTSD, anxiety, or depression by a qualified professional using DSM-5 criteria
- Willing and able to read, understand, and sign informed consent, with clear consciousness and ability to express feelings independently
- Exposed to at least one trauma-focused or evidence-based psychotherapeutic treatment such as prolonged exposure therapy, EMDR, or CBT
- Completed cognitive and psychological assessments
- Clinical diagnosis causes significant impairment in social, occupational, or other functional areas
- Sexually active females of childbearing potential and sexually active males with female partners of childbearing potential must agree to use acceptable contraception during the study and for 30 days after final HBOT session
- Stable on current psychoactive medications including antidepressants, anti-anxiety medications, antipsychotics, stimulants, and mood stabilizers
You will not qualify if you...
- Untreated or history of spontaneous pneumothorax
- Severe sinus infection or upper respiratory infection
- Asymptomatic pulmonary lesions on chest x-ray
- Uncontrollable fever above 39C
- History of chest or ear surgery
- Congenital spherocytosis
- Any anemia or blood disorder
- Any convulsive disorder
- History of optic neuritis or sudden blindness
- Middle ear infection
- Diabetes mellitus requiring insulin therapy
- Pregnant or lactating
- Nicotine use, substance use, or addiction
- Acute hypoglycemia
- Diagnosed chronic obstructive pulmonary disease (COPD) or emphysema
- Symptoms of cough, congestion, vomiting, diarrhea, or open wounds
- Active malignancy
- Current manic, delusional, or psychotic episodes
- Serious or current suicidal ideations
- Severe or unstable physical disorders or major cognitive deficits
- Inability to attend scheduled clinic visits or comply with study protocols
- Previous HBOT treatment before study enrollment
- Non-English speakers
- History of retinal repair procedures or retinal detachment surgery
- History of middle ear surgery including tympanoplasty, mastoidectomy, or pressure equalization tube placement
- Older than 75 years
- Use of medications with known risks interacting with HBOT such as anti-metabolites, chemotherapeutic agents, mafenide acetate, disulfiram, peripheral vasodilators, or certain antibacterial drugs during the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Summit Hyperbarics and Wellness
Boise, Idaho, United States, 83716
Actively Recruiting
Research Team
T
Troy Nickel, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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